An extra pill for OCD slightly helped people rate their time use better
HelpedThe short version
Adding memantine for 16 weeks slightly helped people rate their time use better, but the groups did not start level.
- 60
- adults with OCD
- Randomised
- groups picked at random
- Self-rated
- people rated themselves
- 1 tool
- used
The study
Who took part
60 adults in Iran with moderate to severe OCD. Just over half were women, and the most common age was 29 to 39. They weren't chosen for problems with planning or focus.
What they did
Everyone took the OCD medicine escitalopram every day for 16 weeks. Half also took memantine every day, and half took a dummy pill that looked the same.
What happened
Both groups rated their time management better after 16 weeks, and the memantine group improved slightly more. The groups started at different levels. This was one of six parts of the questionnaire, and the other five parts and OCD symptoms showed no difference. Some of the paper's numbers don't add up.
What the study found
- Helped
Adding memantine for 16 weeks slightly helped people rate their time use better, but the groups did not start level.
Small randomised trial of 60 adults with OCD · vs escitalopram plus a dummy pill · they rated themselves · ⚠ numbers unreliable
How solid is this?
- Groups picked at random
- Plan registered in advance
- Small group
- People rated themselves
- Numbers unreliable
Source
Memantine augmentation of escitalopram in treatment of executive function among patients with obsessive-compulsive disorder (OCD): a double-blind placebo-controlled randomized clinical trial (2025)
DOI: 10.1186/s12888-025-06856-7 (opens in a new tab)
